کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4338003 | 1614833 | 2013 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Odor representation in the olfactory bulb under different brain states revealed by intrinsic optical signals imaging
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کلمات کلیدی
ROIBSRIOS2-Deoxyglucose2-DG - 2 DGElectroencephalography - الکتروانسافالوگرافیOptical imaging - تصویربرداری نوریburst suppression - سرکوب پشت سر همIntrinsic optical signals - سیگنال های نوری ذاتیCorrelation coefficient - ضریب همبستگیEEG - نوار مغزیolfactory bulb - پیاز بویاییBrain states - کشورهای مغز
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Odor representation in the olfactory bulb under different brain states revealed by intrinsic optical signals imaging Odor representation in the olfactory bulb under different brain states revealed by intrinsic optical signals imaging](/preview/png/4338003.png)
چکیده انگلیسی
The olfactory system responds to the same stimulus with great variability according to the current state of the brain. At the levels of multi-unit activity and local field potentials, the response of the olfactory bulb (OB) to a given olfactory stimulus during a state of lower background activity is stronger than the response that occurs during higher background activity, but the distribution pattern of activity remains similar. However, these results have only been established at the individual neuron and neuron cluster scales in previous studies. It remains unclear whether these results are consistent at a larger scale (e.g., OB regions); therefore, intrinsic optical signals imaging was employed in the present study to clarify this issue. The basal brain states of rats were manipulated by using different levels of anesthesia. Under a state of low basal brain activity, the intensity of the activity pattern elicited in the dorsal OB by a given odorant was significantly higher than that under high basal brain activity, but the topography was highly similar across different brain states. These results were consistent across the levels of individual neurons, neuron clusters, glomeruli, and the OB regions, which suggest that the OB contains as yet unknown neural mechanisms that ensure the high-fidelity representation of the same olfactory stimulation under different brain states.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 243, 23 July 2013, Pages 54-63
Journal: Neuroscience - Volume 243, 23 July 2013, Pages 54-63
نویسندگان
J. Lang, A. Li, W. Luo, R. Wu, P. Li, F. Xu,