Keywords: 2-deoxyglucose; Glycolysis; Sonodynamic therapy; Energy metabolism; Breast cancer;
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Keywords: Strawberry; LPS; Human Dermal Fibroblast; Inflammation; Oxidative stress; Antioxidant response; Prevention; 2-DG; 2-deoxyglucose; 2,4 DNP; 2,4-Dinitrophenol; ABB; annexin binding buffer; ABTS; 2,20-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammo
Keywords: ACC; acetyl-CoA carboxylase; ALDOA; aldolase A; AIs; aromatase inhibitors; AMPK; AMP-activated protein kinase; BC; breast cancer; CML; chronic myelogenous leukemia; CT; computed tomography; CPT1; carnitine palmitoyltransferase 1; CRC; colorectal cancer; 2
Keywords: Bicarbonate; HEPES; Buffer; Mitochondria; Respiration; 2DOG; 2-deoxyglucose; DMEM; Dulbecco's modified Eagle's medium; FCCP; trifluorocarbonylcyanide phenylhydrazone; PBS; phosphate-buffered saline;
Keywords: Adrenal; Perifornical hypothalamus; 2-Deoxyglucose; Rostroventrolateral medulla; Sympathetic;
Keywords: Liver cancer; Sonodynamic therapy; 5-aminolevulinic acid; 2-deoxyglucose; Microbubbles;
Keywords: 2-DG; 2-deoxyglucose; AHN; anterior hypothalamic nuclei; COX; cytochrome c oxidase; dACC; dorsal anterior cingulate cortex; HPA; hypothalamic-pituitary-adrenal; LS; lateral septum; MOD; mean optical density; mPFC; medial prefrontal cortex; PAG; periaq
Keywords: 2DG; 2-deoxyglucose; 3MA; 3-methyl adenine; 4E-BP1; Eukaryotic translation initiation factor 4E-binding protein 1; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AMPK; AMP activated protein kinase; ATF4; Activating transcription factor 4; Baf B1; B
Keywords: Synergy; Ferulic acid; Metformin; Anti-diabetic agents; AMPK, PI-3K; Akt; protein kinase B; AMPK; AMP-activated protein kinase; DM; Diabetes mellitus; G6Pase; glucose-6-phosphatase; IRS; Insulin receptor substrate; LD50; lethal dose 50%; PDK-1; 3-phosphoi
Keywords: Metformin; 2-Deoxyglucose; ROS; Autophagy; Feline mammary carcinoma cells;
Keywords: ATP; adenosine triphosphate; BrP; bromopyruvate; CO2; carbon dioxide; CoA; acetyl-coenzyme A; 2-DG; 2-deoxyglucose; ETC; electron transport chain; FAO; fatty acid oxidation; FAD; flavin adenine dinucleotide; FDG; fluorinated deoxyglucose; FFA; free fatty
Keywords: 2-DG; 2-deoxyglucose; 2-HG; 2-hydroxyglutarate; 5mC; 5-methlycystosine; ACACA; acetyl-CoA carboxylase; AML; acute myeloid leukemia; AMPK; adenosine monophosphate-activated protein kinase; ATP; adenosine triphosphate; ALDH; aldehyde dehydrogenase; ADCs; an
Keywords: AAT; aspartate aminotransferase; Ala; alanine; AlaT; alanine aminotransferase; ALD; aldolase; AOA; aminooxyacetate; Asp; aspartate; CS; citrate synthase; 2-DOG; 2-deoxyglucose; DCA; dichloroacetate; DHAP; dihydroxyacetone phosphate; ENO; enolase; Ery4P; e
Keywords: ACSS; acetyl-CoA synthetase; ADI; arginine deiminase; AML; acute myeloid leukaemia; AMPK; AMP-activated protein kinase; ALL; acute lymphoblastic leukaemia; ASS; argininosuccinate synthase; BCAAs; branched-chain amino acids; BPTES; bis-2-(5-phenylacetamido
Keywords: 2DG; 2-deoxyglucose; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle medium; ECAR; extracellular acidification rate; FCCP; trifluorocarbonylcyanide phenylhydrazone; FCS; fetal calf serum; Hepes; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic aci
Keywords: Glycolysis; Cancer; Cell death; GAPDH; Hexokinase; ANT; adenine nucleotide translocase; APAF-1; apoptotic protease activating factor-1; ATG5; autophagy related 5; ATP; adenosine triphosphate; Bak; Bcl-2 homologous antagonistic killer; Bax; Bcl-2-associate
Keywords: Glycolysis; Isoenzymes; Cancer; Spliceforms; Anti-glycolytic agents; Bromopyruvate (PubChem CID: 70684); 2-deoxyglucose (PubChem CID: 9062); 3-PO (PubChem CID: 5720233); PGMI-004A (PubChem CID: 66521681); TEP-46 (Chem CID: 44246499); UDP-GlcNAc; uridine d
Keywords: 2-Deoxyglucose; follicle activation; Foxo3; nutrient deprivation; ovarian reserve;
Keywords: Î2-TGZ; Î2-Troglitazone; TGZ; Troglitazone; TZD; Thiazolidinediones; RGZ; Rosiglitazone; 2-DG; 2-deoxyglucose; ER; endoplasmic reticulum; CGZ; Ciglitazone; UPR; unfolded protein response; Cancer; Glucose metabolism; 2-deoxyglucose, Thiazolidinediones; W
Keywords: AMA; antimycin A; 2-DG; 2-deoxyglucose; Necr-1; necrostatin-1, NSCLC, non-small-cell lung carcinoma; ROS; reactive oxygen species; X/XH; xanthine oxidase/xanthine high concentration; X/XL; xanthine oxidase/xanthine low concentration; ROS; Cell death; Se
Keywords: 2-DG; 2-deoxyglucose; ATP; adenosine triphosphate; FCCP; carbonyl cyanide-4-(trifluoromethoxy) phenylhydrazone; MEF; mouse embryonic fibroblasts; HSF; human skin fibroblasts; MD; mitochondrial diseases; NMR; Nuclear Magnetic Resonance; PEP; phosphoenolpyr
Inhibition of IGF1R enhances 2-deoxyglucose in the treatment of non-small cell lung cancer
Keywords: 2-DG; 2-deoxyglucose; IGF-1R; insulin-like growth factor 1 receptor; NSCLC; non-small cell lung cancer; PARP; poly ADP ribose polymerase; Cancer therapy; Energy metabolism; Insulin-Like growth factor receptor 1 (IGF1R); Lung cancer; Tumor suppressor gene;
Critical role of mammalian target of rapamycin for IL-10 dendritic cell induction by a flagellin AÂ conjugate in preventing allergic sensitization
Keywords: Vaccine; Bet v 1; flagellin; rFlaA; fusion protein; birch pollen allergy; IL-10 dendritic cell; mammalian target of rapamycin; metabolism; alum; Aluminum hydroxide; APC; Antigen-presenting cell; B/A; Bet v 1/alum; DC; Dendritic cell; 2-DO; 2-Deoxyglucose;
IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease
Keywords: Asthma; house dust mite; glycolysis; IL-1; inhibitor of κB kinase ε; lactate; lactate dehydrogenase A; AHR; Airways hyperresponsiveness; BAL; Bronchoalveolar lavage; BMI; Body mass index; DC; Dendritic cell; 2-DG; 2-Deoxyglucose; ECAR; Extracellular aci
Drug resistance induces the upregulation of H2S-producing enzymes in HCT116 colon cancer cells
Keywords: 2-DG; 2-deoxyglucose; 3-MST; 3-mercaptopyruvate sulfurtransferase; 5-FU; 5-fluorouracil; AA; antimycin A; ABC; ATP-binding cassette; AMPK; AMP kinase; AOAA; aminooxyacetic acid; ATM; ataxia-telangiectasia mutated serine/threonine protein kinase; ATP; aden
Glucose dependent miR-451a expression contributes to parathyroid hormone mediated osteoblast differentiation
Keywords: Ovx; Ovariectomy; PTH; Parathyroid Hormone; miRNA; MicroRNA; μCT; Micro-computed tomography; BMD; Bone mineral density; BV/TV; Bone volume/Total volume; SMI; Structural model index; Tb.N; Trabecular number; Conn Dn; Connection density; Tb.Sp; trabecular
FRET-based glucose imaging identifies glucose signalling in response to biotic and abiotic stresses in rice roots
Keywords: eCFP; enhanced cyan fluorescent protein; eYFP; enhanced yellow fluorescent protein; FRET; Förster resonance energy transfer; 2-dG; 2-deoxyglucose; 3-OMG; 3-O-methylglucose; chitin; chitooctaose octahydrochloride; flg22; flagellin 22; FRET nanosensor; Glu
Adenosine isolated from Grifola gargal promotes glucose uptake via PI3K and AMPK signalling pathways in skeletal muscle cells
Keywords: GLF; a low molecular weight fraction of aqueous extract from Grifola gargal; T2DM; type 2 diabetes mellitus; GLUT4; glucose transporter 4; IR; insulin receptor; PI3K; phosphoinositide 3-kinase; 2DG; 2-deoxyglucose; MEM; minimum essential medium; AR; adeno
Endothelial specific SIRT3 deletion impairs glycolysis and angiogenesis and causes diastolic dysfunction
Keywords: SIRT3; PFKFB3; Metabolic reprogram; Coronary microvascular dysfunction; Diastolic dysfunction; 2-DG; 2-deoxyglucose; 3PO; 3-(3-Pyridinyl)-1-(4-pyridinyl)-2-propen-1-one; Ang-1; Angiopoietin-1; CFR; Coronary flow reserve; DHE; Dihydroethidium; ECAR; Extrac
H2S-induced S-sulfhydration of lactate dehydrogenase a (LDHA) stimulates cellular bioenergetics in HCT116 colon cancer cells
Keywords: 2-DG; 2-deoxyglucose; AA; antimycin A; ATP; adenosine triphosphate; CBS; cystathionine-β-synthase; CSE; cystathionine gamma lyase; CTL; control; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GOx; glucose oxidase; H2O2; hydrogen peroxide; H2
Winter to summer change in vitamin D status reduces systemic inflammation and bioenergetic activity of human peripheral blood mononuclear cells
Keywords: 2DG; 2-deoxyglucose; BHI; bioenergetic health index; FBG; fasting blood glucose; FM; fat mass; FFM; fat free mass; IPAQ; international physical activity questionnaire; McA; McAuleys index of insulin sensitivity; PBMCs; peripheral blood mononuclear cells;
Resveratrol induces mitochondrial respiration and apoptosis in SW620 colon cancer cells
Keywords: ÎΨm; mitochondrial membrane potential; 2-DG; 2-deoxyglucose; 5-FU; 5-fluorouracil; ANT A; antimycin A; COX; cytochrome c oxidase; ERα; estrogen receptor alpha; ERβ; estrogen receptor beta; ERRα; estrogen-related receptor alpha; ETO; etomoxir; FCCP; c
PFKFB3, a Direct Target of p63, Is Required for Proliferation and Inhibits Differentiation in Epidermal Keratinocytes
Keywords: 2-DG; 2-deoxyglucose; ChIP; chromatin immunoprecipitation; ECAR; extracellular acidification rate; GFP; green fluorescent protein; nHEK; neonatal human epidermal keratinocyte; PFK1; phosphofructokinase-1; siRNA; small interfering RNA;
1,25(OH)2D3 disrupts glucose metabolism in prostate cancer cells leading to a truncation of the TCA cycle and inhibition of TXNIP expression
Keywords: 1,25(OH)2D3; 1,25-Dihydroxyvitamin D3; 2DG; 2-Deoxyglucose; ACACA; Acetyl CoA carboxylase A; ACC; Acetyl CoA carboxylase; ACLY; ATP citrate lyase; AMPK; AMP-activated protein kinase; AR; Androgen receptor; CAMKK; Ca2Â +-calmodulin-dependent kinase kinase;
Mitochondrial DNA haplogroups modify the risk of osteoarthritis by altering mitochondrial function and intracellular mitochondrial signals
Keywords: ACSS2; acyl-CoA synthetase short-chain family member 2; ALDH1A3; aldehyde dehydrogenase family 1 member A3; AP-1; transcription factor AP-1; BNGE; blue native PAGE; BPGM; 2,3-bisphosphoglycerate mutase; Cybrid; cytoplasmic hybrid; 2-DG; 2-deoxyglucose; DD
Leptin regulates energy metabolism in MCF-7 breast cancer cells
Keywords: Breast cancer; Leptin; Warburg effect; Metabolism; Lipid oxidation; Glycolysis; 2-DG; 2-deoxyglucose; AMPK; 5â² AMP-activated protein kinase; FAT/CD36; fatty acid translocase or cluster of differentiation 36; CPT1; carnitine palmitoyltransferase I; CS; c
Inhibiting Lateral Habenula Improves L-DOPA–Induced Dyskinesia
Keywords: Daun02; 2-Deoxyglucose; Electrophysiology; Macaque; Parkinson’s disease; Rat
Circumventing the Crabtree Effect: A method to induce lactate consumption and increase oxidative phosphorylation in cell culture
Keywords: AMPK; α5â²-adenosine monophosphate-activated protein kinase alpha; ATP5A; ATP synthase subunit alpha; BCA; bicinchoninic acid; FCCP; carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone; COX5B; cytochrome c oxidase subunit 5B; 2-DG; 2-deoxyglucose; GAP
Unraveling the secretome of Termitomyces clypeatus grown on agroresidues as a potential source for bioethanol production
Keywords: TKP; tamarind kernel powder; 2DG; 2deoxyglucose; HPLC; high performance liquid chromatography; GC; gas chromatography; 2D-PAGE; second dimension polyacrylamide gel electrophoresis; EG; endoglucanse; CBH; cellobiohydrolase; PNP; p-nitrophenol; PNPX; p-nitr
Methylisoindigo preferentially kills cancer stem cells by interfering cell metabolism via inhibition of LKB1 and activation of AMPK in PDACs
Keywords: Indirubin; Meisoindigo; Pancreatic cancer stem cell; CSC drug; LKB1 inactivation; AMPK activation; PDAC; CD133; 2-DG; 2-deoxyglucose; ACC; acetyl-CoA carboxylase; AMPK; 5â² AMP-activated protein kinase; CHK2; check point kinase 2; DM; Dorsomorphin; ESA;
Caloric restriction mimetic 2-deoxyglucose alleviated lethal liver injury induced by lipopolysaccharide/d-galactosamine in mice
Keywords: Calorie restriction mimetic; 2-Deoxyglucose; Lipopolysaccharide; Liver injury;
2-Deoxyglucose induces the expression of thioredoxin interacting protein (TXNIP) by increasing O-GlcNAcylation - Implications for targeting the Warburg effect in cancer cells
Keywords: TXNIP; 2-Deoxyglucose; ChoRE; O-GlcNAcylation; MondoA;
Identification of the determinants of 2-deoxyglucose sensitivity in cancer cells by shRNA library screening
Keywords: Warburg effect; 2-Deoxyglucose; shRNA library screening; Glycolysis; Lipolysis
Prenatal protein malnutrition decreases KCNJ3 and 2DG activity in rat prefrontal cortex
Keywords: 2DG; 2-deoxyglucose; 6/25; prenatally malnourished; 25/25; well-nourished controls; ADHD; attention deficit hyperactivity disorder; ANOVA; analysis of variance; GIRK; G protein-gated inwardly rectifying potassium channel; KCNJ3; inward-rectifying potassiu
Uncovering potential of Indonesian medicinal plants on glucose uptake enhancement and lipid suppression in 3T3-L1 adipocytes
Keywords: 2DG; 2-deoxyglucose; BSA; bovine serum albumin; DEX; dexamethasone; DMEM; Dulbecco׳s modified Eagle׳s medium; DMSO; dimethyl sulfoxide; FBS; fetal bovine serum; G6PDH; glucose 6-phosphate dehydrogenase; IBMX; 3-isobutyl-1-methylxanthine; IDF; Internatio
Targeting cholesterol with β-cyclodextrin sensitizes cancer cells for apoptosis
Keywords: Cancer; Phosphoinositide 3-kinase; AKT; Epidermal growth factor; Insulin-like growth factor 1; Receptor tyrosine kinase; Pro-survival signal; Apoptosis; Beta-cyclodextrin; 2-Deoxyglucose; Bcl2; Mcl1; ABT-263; TNF-related apoptosis-inducing ligand; Mitocho
How do changes in the mtDNA and mitochondrial dysfunction influence cancer and cancer therapy? Challenges, opportunities and models
Keywords: ATP; adenosine triphosphate; OXPHOS; oxidative phosphorylation system; mtDNA; mitochondrial DNA; ECT; electron transport chain; nDNA; nuclear DNA; ROS; reactive oxygen species; SODs; superoxide dismutases; MnSOD; manganese superoxide dismutase; GSH; gluta
The anti-angiogenic action of 2-deoxyglucose involves attenuation of VEGFR2 signaling and MMP-2 expression in HUVECs
Keywords: Angiogenesis; 2-Deoxyglucose; Human umbilical vascular endothelial cells; Mannose; Vascular endothelial growth factor receptor-2;
MYC and metabolism on the path to cancer
Keywords: 2-DG; 2-deoxyglucose; 4E-BP; eIF4E-binding protein; 5,10-methylene THF; 5,10-methylenetetrahydrofolate; ACC; acetyl-CoA carboxylase; ACLY; ATP-citrate lyase; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; ChIP-seq; chromatin immunoprecip
Glycerol extends lifespan of Brachionus manjavacas (Rotifera) and protects against stressors
Keywords: Lifespan; Glycerol; Longevity; 2-Deoxyglucose; Swimming;