Role of Aβ-receptor for advanced glycation endproducts interaction in oxidative stress and cytosolic phospholipase A2 activation in astrocytes and cerebral endothelial cells

▶Aβ binding to RAGE to activate NADPH oxidase in endothelial cells and astrocytes. ▶Aβ binding to RAGE to activate cPLA2 in endothelial cells and astrocytes. ▶NADPH oxidase activation is not needed for Aβ to activate cPLA2 in astrocytes.