کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4339654 | 1295763 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Mastication overload causes an increase in O2â production into the subnucleus oralis of the spinal trigeminal nucleus
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کلمات کلیدی
subnucleus caudalisb.w.O2− - O2-ROS - ROSsuperoxide anion - آنیون سوپر اکسیدelectromyography - الکترومیوگرافیEMG - الکترومیوگرافیanalysis of variance - تحلیل واریانسANOVA - تحلیل واریانس Analysis of variancelong term potentiation - تقویت طولانی مدتLTP - تقویت طولانی مدت یا LTP dihydroethidium - دی هیدروتیدیمSubnucleus interpolaris - زیردولت اینترپلاریسsubnucleus oralis - فرعیspinal trigeminal nucleus - هسته سه گانه نخاعیDHE - وbody weight - وزن بدنReactive oxygen species - گونههای فعال اکسیژن
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Mastication overload causes an increase in O2â production into the subnucleus oralis of the spinal trigeminal nucleus Mastication overload causes an increase in O2â production into the subnucleus oralis of the spinal trigeminal nucleus](/preview/png/4339654.png)
چکیده انگلیسی
The aim of the present study was to evaluate the production of superoxide anion (O2â) in the trigeminal complex nuclei after a functional mechanical overload of the teeth due to the preference for masticating on one side in rats. The preference for masticating on one side was induced by the discomfort due to a small abrasion of one molar; such lateralisation in mastication was confirmed by electromyography. The production of O2â was evaluated in the trigeminal nuclei by fluorescence microscopy after an injection of dihydroethidium. The results showed that there was an increased production of O2â in the subnucleus oralis of the spinal trigeminal nucleus in the same side where the mastication was preferred. This result demonstrates that an increased activity of non-painful sensory neurons can enhance the production of reactive oxygen species within the central second order sensory nuclei.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience - Volume 166, Issue 2, 17 March 2010, Pages 416-421
Journal: Neuroscience - Volume 166, Issue 2, 17 March 2010, Pages 416-421
نویسندگان
A. Viggiano, U. Nicodemo, E. Viggiano, G. Messina, A. Viggiano, M. Monda, B. De Luca,