Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish

► Acid-sensing ion channels (ASICs) are involved in acid sensing, and probably also in mechanotransduction, in mammals. ► ASICs were examined by Western blot and immunohistochemistry in the adult zebrafish taste buds. ► ASIC2 and ASIC4 immunoreactivities were detected in taste sensory cells, and ASIC2 in nerves supplying them. ► ASIC1 and ASIC3 were absent from taste buds. ► ASIC2 and ASIC4 could play a role in taste in adult zebrafish.