Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Hippocampus; Learning and memory; Acute stress;
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Keywords: کانال های یون حساس به اسید; Neuroinflammation; Monocytes and T cells; Inflammatory mediators; Matrix mettaloproteinases; Autophagy; ASIC; acid-sensing ion channels; ALS; amyotrophic lateral sclerosis; MMPs; matrix metalloproteases; PD; Parkinson's disease; AD; Alzheimer's Disease; R
Keywords: کانال های یون حساس به اسید; Bioelectronic nose; Bioelectronic tongue; Human olfactory receptor; Human taste receptor; Food quality assessment; AICS; acid-sensing ion channels; BMI; brain-machine interface; CNT; carbon nanotube; CPNT; conducting polymer nanotube; FET; field-effect tr
Keywords: کانال های یون حساس به اسید; AGAP; anti-tumor analgesic peptide; AMPA; α-amino-3-hydroxy-5methylisoxazole-4-propionic acid; ASICs; acid-sensitive ion channels; ATP; adenosine triphosphate; Bmk; toxin isolated from Chinese scorpion Mesobuthus martensii (previously Buthus martensii Ka
Keywords: کانال های یون حساس به اسید; Ischemic stroke; Cerebral ischemia/reperfusion injury; Postconditioning; Neuroprotection; AMPA receptor; 2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl) proprionate receptor; ARE; antioxidant response element; ASICs; Acid-sensing ion channels; BBB; blood brai
Keywords: کانال های یون حساس به اسید; GMQ; 2-guanidine-4-methylquinazoline; ASICs; acid-sensing ion channels; BBB; blood-brain barrier; CHO; Chinese hamster ovary; DMEM; Dulbecco's modified Eagle's medium; acid-sensing ion channel; quercetin; stroke; ischemia; flavonoid; neuroprotection
Keywords: کانال های یون حساس به اسید; Taste buds; Acid-sensing ion channels; Transient receptor potential ion channels; Zebrafish;
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Cephalic lateral line; Neuromasts; Zebrafish; Immunohistochemistry;
Keywords: کانال های یون حساس به اسید; Acid-induced pain; Acid-related gastrointestinal diseases; Acid-sensing ion channels; Acid surveillance; Gastrointestinal tract; Inflammation; Primary afferent neurons; Proton-gated currents; Visceral hypersensitivity;
Antinociceptive activity of ethanolic extract of Azadirachta indica A. Juss (Neem, Meliaceae) fruit through opioid, glutamatergic and acid-sensitive ion pathways in adult zebrafish (Danio rerio)
Keywords: کانال های یون حساس به اسید; EtFrNeem; A. indica fruit ethanolic extract; FT-IR; fourier transform infrared spectroscopy; NMDA; N-methyl-D-aspartate (glutamatergic receptor); ASICs; acid-sensing ion channels; eROS; extracellular reactive oxygen species; 3Rs; ethical principle: reduce
Molecular basis of dental sensitivity: The odontoblasts are multisensory cells and express multifunctional ion channels
Keywords: کانال های یون حساس به اسید; Odontoblasts; Dentin sensitivity; Transient-receptor potential ion channels; Acid-sensing ion channels; ATP; ATP receptors;
ASIC channel inhibition enhances excitotoxic neuronal death in an in vitro model of spinal cord injury
Keywords: کانال های یون حساس به اسید; ANOVA; analysis of variance; ASICs; acid-sensing ion channels; AU; arbitrary unit; DAPI; 4â²,6-diamidino-2-phenylindole; DIV; days in vitro; DME/HIGH; Dulbecco's modified Eagle's medium high glucose; DR; dorsal root; FCS; fetal calf serum; KA; kainat
Histamine selectively potentiates acid-sensing ion channel 1a
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; BSA; bovine serum albumin; CHO cells; Chinese hamster ovary cells; NMDA; N-methyl-d-aspartate; PcTx1; psalmotoxin 1; ASIC; Histamine; Potentiation; Selectivity;
Potentiation of acid-sensing ion channel activity by peripheral group I metabotropic glutamate receptor signaling
Keywords: کانال های یون حساس به اسید; ASIC; acid-sensing ion channels; DRG; dorsal root ganglion; IpH; proton-gated current; mGluR; smetabotropic glutamate receptors; PICK1; protein interacting with C-kinase 1; PKC; protein kinase C; PLC; phospholipase C; TRPV1; transient receptor potential v
Research reportAcid modulation of tetrodotoxin-sensitive Na+ channels in large-sized trigeminal ganglion neurons
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; DRG; dorsal root ganglia; INa; Na+ currents; [Na+]o; extracellular Na+ concentration; Ïfast; fast time constants; Ïslow; slow time constants; ÏWD or Ïweighted; weighted time constant; TG; trigeminal ganglia; TTX-R; te
Interleukin-6 enhances acid-induced apoptosis via upregulating acid-sensing ion channel 1a expression and function in rat articular chondrocytes
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; ASIC1a; acid-sensing ion channel 1a; AA; adjuvant arthritis; IL-6; interleukin-6; RA; rheumatoid arthritis; JAK; janus kinase; STAT; signal transducer and activator of transcription; MAPK; mitogen-activated protein kinase
14th Annual Meeting of the Safety Pharmacology Society: Threading through peripheral and central nervous system presentations
Keywords: کانال های یون حساس به اسید; Aβ; Aβ-amyloid protein; AANEM; American Academy of Neuromuscular and Electrodiagnostic Medicine; AAN; American Academy of Neurology; AD; Alzheimer's Disease; API; Alzheimer's Prevention Initiative-APOE4; ADF; Abuse Deterrent Formulations; ADNI; Alzheime
Differences in acid-induced currents between oxytocin-mRFP1 and vasopressin-eGFP neurons isolated from the supraoptic and paraventricular nuclei of transgenic rats
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Fluorescent protein; SON; PVN; Oxytocin; Vasopressin;
Potentiated macrophage activation by acid sensing under low adiponectin levels
Keywords: کانال های یون حساس به اسید; Adiponectin; Acid-sensing ion channels; Na+/Ca2+ exchangers; Adiponectin anti-sense transgenic mice; Macrophages; Inflammation; MΦ; macrophage; AsTg; adiponectin anti-sense transgenic; ASICs; acid-sensing ion channels; NCXs; Na+/Ca2+ exchangers; HBSS; HE
Extracellular pH modulates GABAergic neurotransmission in rat hypothalamus
Keywords: کانال های یون حساس به اسید; ACSF; artificial cerebral-spinal fluid; ANOVA; analysis of variance; ASICs; acid-sensing ion channels; EGTA; ethylene glycol tetraacetic acid, HEPES, 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; IPSC; inhibitory postsynaptic current; MES; 2-ethanes
ReviewBDNF: No gain without pain?
Keywords: کانال های یون حساس به اسید; ASIC1a; acid-sensing ion channels; BDNF; brain-derived neurotrophic factor; CCI; chronic constriction injury; DRG; dorsal root ganglia; ERK; extracellular signal-related kinase; KCC2; K+-Clâ cotransporter; MOR; mu-opioid receptor; p75NTR; p75 neurotroph
The Deakin/Graeff hypothesis: Focus on serotonergic inhibition of panic
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Amygdala; Carbon dioxide; Corticotropin-releasing hormone; Dorsal raphe nucleus; Panic attack; Panic disorder; Periaqueductal gray; Serotonin; Sodium lactate; Stress; TASK
Differential regulation of locomotor activity to acute and chronic cocaine administration by acid-sensing ion channel 1a and 2 in adult mice
Keywords: کانال های یون حساس به اسید; ASIC1a; acid-sensing ion channel 1a; ASIC2; acid-sensing ion channel 2; ASICs; acid-sensing ion channels; KO; knockout; WT; wild-type; acid-sensing ion channels; cocaine; stimulant; addiction; locomotor activity; behavioral sensitization;
Acid-sensing ion channels (ASICs) in the taste buds of adult zebrafish
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Taste buds; Zebrafish;
Evaluating a novel analgesic strategy for ring castration of ram lambs
Keywords: کانال های یون حساس به اسید; acid-sensing ion channels; cortisol; non-steroidal anti-inflammatory; ring castration; sheep;
Stress and visceral pain: From animal models to clinical therapies
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; BDNF; brain-derived neutrophic factor; ATP; adenosine triphosphate; CB; cannabinoid; CeA; central amygdala; CNS; central nervous system; CRD; colorectal distension; CRF; corticotropin releasing factor; CRF1; CRF receptor
Acid-sensing ion channel 2 (ASIC2) in the intestine of adult zebrafish
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Zebrafish; Enteric nervous system; Enteroendocrine cells
Regulation of acid-sensing ion channel 1a function by tissue kallikrein may be through channel cleavage
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Tissue kallikrein; Channel cleavage; Function; Regulatory mechanisms
Research ReportNeuroprotective effect of sophocarpine against transient focal cerebral ischemia via down-regulation of the acid-sensing ion channel 1 in rats
Keywords: کانال های یون حساس به اسید; Sophocarpine; Acid-sensing ion channel; Neuroprotection; Ischemic stroke; Middle cerebral artery occlusion; SC; sophocarpine; ASICs; acid-sensing ion channels; MCAO; middle cerebral artery occlusion; TTC; 2,3,5-triphenyl tetrazolium chloride; TUNEL; termi
Research ReportPossible contribution of pannexin channel to ATP-induced currents in vitro in vasopressin neurons isolated from the rat supraoptic nucleus
Keywords: کانال های یون حساس به اسید; ASIC; acid-sensing ion channels; AVP; arginine vasopressin; CBX; carbenoxolone; eGFP; enhanced green fluorescent protein; FFA; flufenamic acid; HBS; HEPES buffer solution; KHB; Krebs-Henseleit solution; MFQ; mefloquine; MNC; magnocellular neurosecretory
Psychopharmacology: A house divided
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; ADs; antidepressants; APs; antipsychotics; βARs; beta-adrenergic receptors; BDNF; brain-derived neurotrophic factor; CRS; chronic restraint stress; CDS; chronic social defeat stress; CREB; cyclic-AMP response-element-bin
Cysteine 149 in the extracellular finger domain of acid-sensing ion channel 1b subunit is critical for zinc-mediated inhibition
Keywords: کانال های یون حساس به اسید; acid-sensing ion channels; zinc; ASIC1b; patch-clampACCN2, amiloride-sensitive cation channel 2, neuronal; ASICs, acid-sensing ion channels; ASIC1b, acid-sensing ion channel 1b; ASICβ, acid-sensing ion channel β; CHO, Chinese hamster ovary; CTRL, control;
ASICs aggravate acidosis-induced injuries during ischemic reperfusion
Keywords: کانال های یون حساس به اسید; ASICs; acid-sensing ion channels; AV; annexin V; DMEM; Dulbecco's modified Eagle's medium; EDTA; ethylene glycol tetraacetic acid; MTT; 3-(4,5)-dimethylthiahiazo(-z-y1)-3,5-di-phenytetrazoliumromide; OGD; oxygen and glucose deprivation; PBS; phosphate-buf
Inhibitory regulation of acid-sensing ion channel 3 by zinc
Keywords: کانال های یون حساس به اسید; acid-sensing ion channels; zinc; ASIC3; sensory neurons; patch-clampASICs, acid-sensing ion channels; ASIC3, acid-sensing ion channel 3; CHO, Chinese hamster ovary; CTRL, control; DRG, dorsal root ganglia; ECF, extracellular fluid; IC50, half of maximum i
Acid-Sensing Ion Channel 3 Expression in Mouse Knee Joint Afferents and Effects of Carrageenan-Induced Arthritis
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; joint; pain; dorsal root ganglion; inflammation; acid; calcitonin gene-related peptide
Characterization of acid-sensing ion channels in medium spiny neurons of mouse striatum
Keywords: کانال های یون حساس به اسید; striatum; acid-sensing ion channels; medium spiny neurons; membrane excitability; patch-clamp; calcium imagingASIC, acid-sensing ion channel; [Ca2+]i, intracellular Ca2+ concentrations; CNQX, 6-cyano-7-nitroquinoxalinee-2,3-dione; ECF, extracellular solut
Tissue kallikrein protects cortical neurons against in vitro ischemia-acidosis/reperfusion-induced injury through the ERK1/2 pathway
Keywords: کانال های یون حساس به اسید; Cortical neurons; Tissue kallikrein; Acidosis; Acid-sensing ion channels; Oxygen and glucose deprivation; Oxidative stress; Extracellular signal-regulated kinase1/2 signaling pathways
Direct visualization of the trimeric structure of the ASIC1a channel, using AFM imaging
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Channel assembly; Subunit stoichiometry; Atomic force microscopy
Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Gastric acid hyperresponsiveness; Gastritis; Expression of c-Fos; Nucleus of the solitary tract; Vagal afferent neurons;
Identification of acid-sensing ion channels in adenoid cystic carcinomas
Keywords: کانال های یون حساس به اسید; Acid-sensing ion channels; Adenoid cystic carcinomas; Patch-clamp; RT-PCR; Western blotting;
Modulation of acid-sensing ion channels by Cu2+ in cultured hypothalamic neurons of the rat
Keywords: کانال های یون حساس به اسید; acid-sensing ion channels; Cu2+; hypothalamus; patch clamp; membrane excitabilityANOVA, analysis of variance; ASIC, acid-sensing ion channel; C, drug concentration; EC50, agonist concentration inducing half-maximal response; EDTA, ethylenediaminetetraacet
The development of an innervated epithelial barrier model using a human corneal cell line and ND7/23 sensory neurons
Keywords: کانال های یون حساس به اسید; ND7/23 sensory neurons; Human corneal cell line; Calcium-regulated adhesion molecules; Acid-sensing ion channels; Patch-clamp;