5′-Aza-dC sensitizes paraquat toxic effects on PC12 cell

► Paraquat plus 5′-aza-dC treatment decreased cell activity remarkably. ► Paraquat plus 5′-aza-dC treatment increased apoptotic cells remarkably. ► Paraquat plus 5′-aza-dC treatment increased ROS levels significantly. ► Paraquat plus 5′-aza-dC treatment increased mitochondrial apoptotic proteins expression.