Analysis of methylprednisolone-induced inhibition on the proliferation of neural progenitor cells in vitro by gene expression profiling

► It was confirmed in vitro that methylprednisolone had proliferation inhibition effect on NPCs. ► We analyzed the differentially expressed genes induced by methylprednisolone in NPCs. ► Global molecular insights into the mechanisms of proliferation inhibition effect were provided. ► EdnrB may play a vital role in the proliferation inhibition effect.