Neuroprotective effects of olprinone after cerebral ischemia/reperfusion injury in rats

► Stroke causes partial paralysis, difficulties with memory, language and movements. ► Olprinone is characterized by positive inotropic and vasodilator actions. ► Olprinone, a phosphodiesterase III inhibitor, has anti-inflammatory effects. ► Olprinone has been confirmed to exert direct neuroprotective effects.