NGF protects Dorsal Root Ganglion neurons from oxaliplatin by modulating JNK/Sapk and ERK1/2

▶ NGF and RA neuroprotective effect depends on JNK/Sapk and ERK1/2 activation. ▶ ERK activation is both prodifferentiative and proapoptotic. ▶ Agents promoting JNK/Sapk and ERK activation are potentially neuroprotective.