کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4346298 1296781 2010 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessing the role of the medial preoptic area in ethanol-induced hypothermia
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Assessing the role of the medial preoptic area in ethanol-induced hypothermia
چکیده انگلیسی
Administration of ethanol produces hypothermia. The preoptic area/anterior hypothalamus (POA/AH) contains warm- and cold-sensitive neurons that are important for temperature regulation. The present study evaluated the effect of ethanol on Fos immunoreactivity (Fos-ir) in the medial preoptic area (MPOA) and the effect of lesions to the MPOA on ethanol-induced hypothermia. Rats receiving 1.5-g/kg ethanol showed an increase in Fos-ir in the MPOA. However, lesions to the MPOA did not affect core body temperature. These findings indicate that ethanol increases neural activity in the MPOA, but this increased activity does not influence ethanol-induced changes in core body temperature.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 475, Issue 1, 7 May 2010, Pages 25-28
نویسندگان
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