کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4349477 1296943 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Neurogenesis and major depression: implications from proteomic analyses of hippocampal proteins in a rat depression model
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Neurogenesis and major depression: implications from proteomic analyses of hippocampal proteins in a rat depression model
چکیده انگلیسی

Major depression is one of the most disabling disorders. Yet, the pathogenesis of this mental disorder is poorly understood. Hippocampus is generally believed to be associated with pathogenesis of depression. In this study, we adopted a proteomic approach to examine possible alterations of protein expression in the hippocampus of a rat depression model. Our results suggest that neurogenesis in hippocampus may play an important role in the pathogenesis of major depression.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 416, Issue 3, 18 April 2007, Pages 252–256
نویسندگان
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