کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4349879 1296962 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Deactivation and activation of left frontal lobe during and after low-frequency repetitive transcranial magnetic stimulation over right prefrontal cortex: A near-infrared spectroscopy study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
Deactivation and activation of left frontal lobe during and after low-frequency repetitive transcranial magnetic stimulation over right prefrontal cortex: A near-infrared spectroscopy study
چکیده انگلیسی

The effects of low-frequency repetitive transcranial magnetic stimulation (rTMS) over the right frontal lobe on the function of the left frontal lobe were examined by near-infrared spectroscopy (NIRS) in eleven healthy subjects. rTMS applied 5 cm anterior to the motor cortex at 1 Hz and approximately 50% of the motor threshold intensity (MT) for 60 s resulted in a significantly larger decrease in the concentration of oxygenated hemoglobin ([oxy-Hb]) during the stimulation period followed by a significantly larger increase in [oxy-Hb] and a smaller decrease in the concentration of deoxygenated hemoglobin ([deoxy-Hb]) during the poststimulation baseline period than sham stimulation. These findings are interpreted as demonstrating the deactivation and activation of the left frontal cortex during and after rTMS of the right frontal cortex, respectively. If replicated in depressed patients, NIRS can be employed for monitoring rTMS effects as brain [Hb] changes in vivo, and may be helpful for determining therapeutic parameters of rTMS for individual patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 414, Issue 2, 6 March 2007, Pages 99–104
نویسندگان
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