کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4350407 | 1615188 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Tic distribution and inhibitory processes in the sensorimotor circuit during adolescence: A cross-sectional TMS study
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Tic distribution and inhibitory processes in the sensorimotor circuit during adolescence: A cross-sectional TMS study Tic distribution and inhibitory processes in the sensorimotor circuit during adolescence: A cross-sectional TMS study](/preview/png/4350407.png)
چکیده انگلیسی
Deficient inhibitory processes within the sensorimotor circuit, reflected by a shortened cortical silent period (CSP), have previously been described in both children and adults with tic disorders (TD) using transcranial magnetic stimulation (TMS). In contrast to adults, tic distribution (presence or absence of distal tics) did not affect CSP duration in children. The aim of this developmental TMS study was to clarify this striking difference. 127 children with TD were stratified into three age-groups (8-11.5, 11.5-15, 15-19 years) with and without distal tics. CSP was recorded from the abductor digiti minimi. Statistics revealed a significant tic distribution Ã age interaction effect. Only in the 15-19 years subgroup, CSP was shorter in patients with distal tics in comparison to patients without distal tics (94.1 ± 54.1 ms versus 135.2 ± 36.8 ms at a stimulus intensity of active motor threshold plus 30%). Inhibitory processes in the sensorimotor circuit could reflect developmental aspects of tic phenomenology, particularly tic distribution during adolescence.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 403, Issues 1â2, 31 July 2006, Pages 96-99
Journal: Neuroscience Letters - Volume 403, Issues 1â2, 31 July 2006, Pages 96-99
نویسندگان
Gunther H. Moll, Hartmut Heinrich, Holger Gevensleben, Aribert Rothenberger,