کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4350455 | 1296986 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of electroconvulsive seizures on Na+,K+-ATPase activity in the rat hippocampus
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effects of electroconvulsive seizures on Na+,K+-ATPase activity in the rat hippocampus Effects of electroconvulsive seizures on Na+,K+-ATPase activity in the rat hippocampus](/preview/png/4350455.png)
چکیده انگلیسی
Although several advances have occurred concerning the use of electroconvulsive therapy, little progress has been made in understanding the mechanisms underlying its therapeutic or side effects. Na+,K+-ATPase is an important enzyme of central nervous system, responsible for ionic gradient maintenance and consumption of approximately 40-50% of brain ATP. This work was performed in order to determine Na+,K+-ATPase activity after acute and chronic electroconvulsive shock. Results showed an inhibition of Na+,K+-ATPase activity in the hippocampus 48Â h, 7, 30, 60 and 90 days after a single electroconvulsive shock. Chronic treatment diminished the enzyme activity in the hippocampus 7 and 30 days after electroconvulsive (ECS) sessions. Our findings demonstrated that Na+,K+-ATPase activity is altered by ECS.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 404, Issue 3, 1 September 2006, Pages 254-257
Journal: Neuroscience Letters - Volume 404, Issue 3, 1 September 2006, Pages 254-257
نویسندگان
Emilio L. Streck, Gustavo Feier, Márcio Búrigo, Renata Franzon, Felipe Dal-Pizzol, João Quevedo, Angela T.S. Wyse,