کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4350455 | 1296986 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effects of electroconvulsive seizures on Na+,K+-ATPase activity in the rat hippocampus
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Although several advances have occurred concerning the use of electroconvulsive therapy, little progress has been made in understanding the mechanisms underlying its therapeutic or side effects. Na+,K+-ATPase is an important enzyme of central nervous system, responsible for ionic gradient maintenance and consumption of approximately 40-50% of brain ATP. This work was performed in order to determine Na+,K+-ATPase activity after acute and chronic electroconvulsive shock. Results showed an inhibition of Na+,K+-ATPase activity in the hippocampus 48Â h, 7, 30, 60 and 90 days after a single electroconvulsive shock. Chronic treatment diminished the enzyme activity in the hippocampus 7 and 30 days after electroconvulsive (ECS) sessions. Our findings demonstrated that Na+,K+-ATPase activity is altered by ECS.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 404, Issue 3, 1 September 2006, Pages 254-257
Journal: Neuroscience Letters - Volume 404, Issue 3, 1 September 2006, Pages 254-257
نویسندگان
Emilio L. Streck, Gustavo Feier, Márcio Búrigo, Renata Franzon, Felipe Dal-Pizzol, João Quevedo, Angela T.S. Wyse,