کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4350792 | 1615192 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Recovery after a traumatic brain injury depends on diurnal variations: Effect of cystatin C
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
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چکیده انگلیسی
Many studies indicate that the hour of the day at which the onset of stroke occurs is very important in patient recovery. Furthermore, multiple studies have been conducted which show that ischemia in rats produces different magnitudes of injury depending on the hour of the day at which it was induced. Using a traumatic brain injury (TBI) model, we analyzed the effect of the time of day on the recovery of rats and obtained a higher survival rate if TBI was induced at 01:00 h as compared with TBI induced at 13:00 h. We also analyzed the effect of the protease inhibitor cystatin C (CC) on the recovery of rats from TBI and found that it increased mortality and bleeding, and that these effects were more pronounced at 13:00 h.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 400, Issues 1–2, 29 May 2006, Pages 21–24
Journal: Neuroscience Letters - Volume 400, Issues 1–2, 29 May 2006, Pages 21–24
نویسندگان
Marina Martinez-Vargas, Ruben Gonzalez-Rivera, Maribel Soto-Nuñez, Marina Cisneros-Martinez, Alejandro Huerta-Saquero, Julio Morales-Gomez, Juan Molina-Guarneros, Luz Navarro,