کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4352348 | 1298108 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Association study of polymorphisms in N-methyl-d-aspartate receptor 2B subunits (GRIN2B) gene with Korean alcoholism
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Association study of polymorphisms in N-methyl-d-aspartate receptor 2B subunits (GRIN2B) gene with Korean alcoholism Association study of polymorphisms in N-methyl-d-aspartate receptor 2B subunits (GRIN2B) gene with Korean alcoholism](/preview/png/4352348.png)
چکیده انگلیسی
The N-methyl-d-aspartate (NMDA) receptor 2B gene (GRIN2B) was studied as a candidate gene of alcoholism. This study aimed to investigate the association between each of the three GRIN2B polymorphisms (rs1806201, rs1805247, and rs1805502) and alcoholism. This study included 206 alcoholic patients and 189 unrelated control subjects of Korean origin. Associations between genotype, allele, and haplotype frequencies of the polymorphisms and alcoholism were investigated. The genotype frequencies of rs1806201 and the haplotype analysis of SNPs in this study show significantly differences between the case and controls. These findings suggest new candidate SNPs in GRIN2B for studying the genetic susceptibility to alcoholism.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Research - Volume 56, Issue 2, October 2006, Pages 220-223
Journal: Neuroscience Research - Volume 56, Issue 2, October 2006, Pages 220-223
نویسندگان
Jin Hee Kim, Mira Park, So Young Yang, Bum Seok Jeong, Hee Jeong Yoo, Jong-Woo Kim, Joo-Ho Chung, Soon Ae Kim,