کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4355143 1615590 2014 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Auditory responses to electric and infrared neural stimulation of the rat cochlear nucleus
ترجمه فارسی عنوان
پاسخ های شنیداری به تحریک عصبی الکتریکی و مادون قرمز هسته حلقوی موش
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
چکیده انگلیسی


• Electric and infrared neural stimulation (INS) was applied to the cochlear nucleus.
• Electric stimulation elicited collicular and auditory brainstem responses (ABRs).
• INS also elicited colliculular responses & ABRs similar to acoustically-evoked ABRs.
• Deafening decreased INS responses, suggesting their generation by a laser artifact.

In an effort to improve the auditory brainstem implant, a prosthesis in which user outcomes are modest, we applied electric and infrared neural stimulation (INS) to the cochlear nucleus in a rat animal model. Electric stimulation evoked regions of neural activation in the inferior colliculus and short-latency, multipeaked auditory brainstem responses (ABRs). Pulsed INS, delivered to the surface of the cochlear nucleus via an optical fiber, evoked broad neural activation in the inferior colliculus. Strongest responses were recorded when the fiber was placed at lateral positions on the cochlear nucleus, close to the temporal bone. INS-evoked ABRs were multipeaked but longer in latency than those for electric stimulation; they resembled the responses to acoustic stimulation. After deafening, responses to electric stimulation persisted, whereas those to INS disappeared, consistent with a reported “optophonic” effect, a laser-induced acoustic artifact. Thus, for deaf individuals who use the auditory brainstem implant, INS alone did not appear promising as a new approach.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 310, April 2014, Pages 69–75
نویسندگان
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