کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4358592 1300443 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Re-sequencing of a virulent strain of Campylobacter jejuni NCTC11168 reveals potential virulence factors
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Re-sequencing of a virulent strain of Campylobacter jejuni NCTC11168 reveals potential virulence factors
چکیده انگلیسی

In vitro passage of Campylobacter jejuni strains results in phenotypic changes and a general loss of virulence, as is the case with the genome-sequenced strain C. jejuni NCTC11168. Re-sequencing of a virulent strain of NCTC11168 identified 41 SNPs or indels involving 20 genes, four intergenic regions and three pseudogenes. The genes include six motility genes, two chemotaxis genes, three hypothetical genes and a capsule biosynthesis gene, which might have a critical role in C. jejuni virulence. Additionally, we found an insertion in both Cj0676 and Cj1470c, pseudogenes in avirulent NCTC11168, but functional proteins in virulent NCTC11168.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Microbiology - Volume 164, Issue 1, January 2013, Pages 6–11
نویسندگان
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