کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4359524 | 1300515 | 2006 | 10 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Cytological and biochemical evidence for an early cell dismantling event in surface cultures of Streptomyces antibioticus Cytological and biochemical evidence for an early cell dismantling event in surface cultures of Streptomyces antibioticus](/preview/png/4359524.png)
A process of programmed cell death taking place late in the aerial mycelium was previously reported in surface cultures of Streptomyces antibioticus ATCC11891. In this study, we present evidence for the occurrence of a similar process taking place early in the vegetative mycelium of surface cultures of the same strain. Several indicators, such as cell wall and membrane disruption, DNA degradation and release of the cytoplasmic content into the exocellular medium, support the existence of active, highly regulated cell suicide involving specific enzymes. Calcium-dependent proteolytic activation of a precursor of nucleases and the nucleolytic formation of a ladder of chromosomal bands are conspicuous events associated with the initiation of the death process.
Journal: Research in Microbiology - Volume 157, Issue 2, March 2006, Pages 143-152