Comparison of 1-step and 2-step methods of fitting microbiological models

► 1-step and traditional 2-step model fitting methods are compared. ► 1-step fitting is better in every way. ► 1-step fitting is possible whenever 2-step fitting can be used, and sometimes when it cannot. ► Modern computers make 1-step fitting straightforward. ► 1-step should replace 2-step as the normal fitting method.