کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4371930 1302550 2009 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Malaria antigen-mediated enhancement of interleukin-21 responses of peripheral blood mononuclear cells in African adults
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Malaria antigen-mediated enhancement of interleukin-21 responses of peripheral blood mononuclear cells in African adults
چکیده انگلیسی

We recently showed that IL-21 is associated with high level of anti-EBA-175 IgG1 and IgG3. Here we have investigated the ability of two malarial antigens, Glutamate-rich protein and merozoite surface protein 3 to induce IL-21 production from PBMCs from malaria-exposed and non-exposed donors. We found that malaria-exposed donors produced significantly more IL-21 compared to non-exposed donors. These data suggest that IL-21 could be involved in the acquisition of immunity to malaria.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Parasitology - Volume 122, Issue 1, May 2009, Pages 37–40
نویسندگان
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