Glucose metabolism in the hepatopancreas of the crab Neohelice granulata maintained on carbohydrate-rich or high-protein diets: Anoxia and recovery

► We investigated the effects of anoxia and recovery on hepatopancreatic glucose metabolism in the crab Neohelice granulata fed on either a carbohydrate-rich (HC) or high-protein (HP) diet. ► Anoxia increased pyruvate kinase (PK) and hexokinase (HK) activities in HC-fed animals. No significant changes occurred in glucose uptake and glycogen synthesis in either dietary group. ► In HP-fed crabs, HK activity decreased and PK activity was 40% lower than that found in the HC-fed group after anoxia. ► Anoxia decreased 14CO2 production, ATP and glycogen levels in hepatopancreas in both groups. ► In HC-fed crabs, the hepatopancreas glycolytic pathway is involved in the post-anoxia fate of glucose.