کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4421308 | 1308509 | 2010 | 7 صفحه PDF | دانلود رایگان |
In nematodes, 10 J/m2/min of UV irradiation induced a mild reproductive toxicity. Pre-treatment with UV irradiation at 10 J/m2/min suppressed the formation of reproductive defects, and activated a noticeable reduction of percentage of population with hsp-16.2::gfp expression, an obvious elevation of superoxide dismutase activities, and decrease of oxidative damage in 50 and 100 μM Cd exposed nematodes; however, pre-treatment with UV irradiation at 20 J/m2/min caused a significant decrease of brood sizes or increase of generation times in Cd-exposed nematodes. Pre-treatment with mild UV irradiation did not suppress the formation of reproductive defects in 150 μM Cd-exposed nematodes. Furthermore, the adaptive response to reproductive toxicity from Cd exposure was not observed in a reactive oxygen species sensitive mev-1(kn1) mutant. Therefore, pre-treatment with mild UV irradiation triggers the resistance to reproductive toxicity from Cd exposure by at least partially inducing adaptation to oxidative stress and through a mev-1-dependent pathway.
Journal: Ecotoxicology and Environmental Safety - Volume 73, Issue 3, March 2010, Pages 423–429