کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4423381 | 1308822 | 2010 | 12 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Non-cancer effects of formaldehyde and relevance for setting an indoor air guideline
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
شیمی زیست محیطی
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چکیده انگلیسی
Concentrations of FA, both personal and stationary, are on average in the order of 0.05Â mg/m3 or less in Europe and North America with the exception of new housing or buildings with extensive wooden surfaces, where the concentration may exceed 0.1Â mg/m3. With the eye the most sensitive organ, subjective irritation is reported at 0.3-0.5Â mg/m3, which is somewhat higher than reported odour thresholds. Objective effects in the eyes and airways occur around 0.6-1Â mg/m3. Dose-response relationships between FA and lung function effects have not been found in controlled human exposure studies below 1Â mg/m3, and epidemiological associations between FA concentrations and exacerbation of asthma in children and adults are encumbered by complex exposures. Neither experimental nor epidemiological studies point to major differences in susceptibility to FA among children, elderly, and asthmatics. People with personal trait of negative affectivity may report more symptoms. An air quality guideline of 0.1Â mg/m3 (0.08Â ppm) is considered protective against both acute and chronic sensory irritation in the airways in the general population assuming a log normal distribution of nasal sensory irritation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environment International - Volume 36, Issue 7, October 2010, Pages 788-799
Journal: Environment International - Volume 36, Issue 7, October 2010, Pages 788-799
نویسندگان
Peder Wolkoff, Gunnar D. Nielsen,