کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4425315 | 1309099 | 2011 | 9 صفحه PDF | دانلود رایگان |

Biomarkers comprising activities of biotransformation enzymes (ethoxyresorufin-O-deethylase –EROD–, dibenzylfluorescein dealkylase –DBF–, glutathione S-transferase –GST), antioxidant enzymes (glutathione reductase –GR– and glutathione peroxidase –GPX), lipid peroxidation –LPO– and DNA strand breaks were analyzed in the clam Ruditapes philippinarum caged at Cádiz Bay, Santander Bay and Las Palmas de Gran Canaria (LPGC) Port (Spain). Sediments were characterized. Digestive gland was the most sensitive tissue to sediment contamination. In Cádiz Bay, changes in LPO regarding day 0 were related with metals. In LPGC Port, DBF, EROD, and GST activity responses suggested the presence of undetermined contaminants which might have led to DNA damage. In Santander Bay, PAHs were related with EROD activity, organic and metal contamination was found to be associated with GR and GST activities and DNA damage presented significant (p < 0.05) induction. R. philippinarum was sensitive to sediment contamination at biochemical level. Biomarkers allowed chemical exposure and sediment quality assessment.
► Ruditapes philippinarum is sensitive to sediment contamination at biochemical level.
► Digestive gland biomarkers showed the best correlations with sediment contaminants.
► Presence of potentially toxic chemicals not analyzed in this research was unmasked.
► Multivariate analysis allowed the identification of toxic xenobiotic and possible sources.
► Inner area of Santander Bay presented the highest sediment toxicity.
Journal: Environmental Pollution - Volume 159, Issue 7, July 2011, Pages 1914–1922