کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4429463 1619825 2012 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemical fate and genotoxic risk associated with hypochlorite treatment of nicotine
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Chemical fate and genotoxic risk associated with hypochlorite treatment of nicotine
چکیده انگلیسی

Nicotine, the main alkaloid of tobacco, is a non- prescription drug to which all members of a tobacco-smoking society are exposed either through direct smoke inhalation or through second-hand passive ‘smoking’. Nicotine is also commercially available in some pharmaceutical products and is used worldwide as a botanical insecticide in agriculture. Nicotine dynamics in indoor and outdoor environments as well as the human excretions and the manufacturing process are responsible for its entry in the environment through municipal and industrial wastewater discharges. The presence of nicotine in surface and ground waters points out that it survives a conventional treatment process and persists in potable-water supplies. Complete removal of nicotine is instead reported when additional chlorination steps are used.In this paper a simulation of STP chlorination of nicotine and a genotoxic evaluation of its main degradation products are reported. Under laboratory conditions removal of nicotine seems not to be due to mineralization but to transformation in oxidized and chlorinated products. The by-products have been isolated after fractionation by diverse chromatographic procedures and their structures determined using mass spectrometry and 1H and 13C NMR spectroscopy. Preliminary genotoxic SOS Chromotests with Escherichia coli PQ37 evidence no toxicity of the products.


► Processes of chlorination in the treatment of raw water.
► STP chlorination of nicotine.
► Genotoxic evaluation of main degradation products of nicotine.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Science of The Total Environment - Volume 426, 1 June 2012, Pages 132–138
نویسندگان
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