کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4435164 1620141 2015 16 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Chemistry of natural waters and its relation to Buruli ulcer in Ghana
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات فرآیندهای سطح زمین
پیش نمایش صفحه اول مقاله
Chemistry of natural waters and its relation to Buruli ulcer in Ghana
چکیده انگلیسی

Study regionBuruli ulcer, an emerging disease caused by Mycobacterium ulcerans, largely affects poor rural populations in tropical countries. The environmental niche that supports this necrotizing bacterium is unclear. Here, water samples were collected from five communities within Ghana in the rainy season in 2011: four in the southern part of Ghana (three disease-endemic communities: Pokukrom, Betenase, and Ayanfuri, and one control: Kedadwen) and one non-endemic community (Nangruma) in the north.Study focusPast studies of Buruli ulcer conclude that water quality is, in some way, closely related to the transmission of this disease. This work serves as a first step to explore links between Buruli ulcer incidence and water quality. More broadly, this research works toward identifying the environmental niche for M. ulcerans, providing characterization of water bodies hazardous to human health in at-risk communities.New hydrological insightsTrace metals, thought to aid in the preferential growth of M. ulcerans, are present in higher concentrations in mining pits and stagnant pools than in other tested water bodies. Arsenic in particular could serve as a double threat for BU incidence: it could support the growth of M. ulcerans while suppressing immune systems, making the population more susceptible to disease. Few other differences between endemic and non-endemic communities exist, implying other variables such as human behavior may also control the onset of Buruli ulcer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Hydrology: Regional Studies - Volume 3, March 2015, Pages 457–472
نویسندگان
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