کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4513618 | 1624865 | 2013 | 7 صفحه PDF | دانلود رایگان |
In the present work, the phenolic compounds of Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers from Northeastern Portugal were characterized by HPLC–DAD–ESI/MS. Furthermore, it was performed a screening of their antifungal potential against Candida species (Candida albicans, Candida glabrata, Candida parapsilosis and Candida tropicalis).C. sativa sample gave the highest amount of phenolic compounds (18973 ± 40 μg/g, fw) and hydrolysable tannins (14873 ± 110 μg/g). The highest amounts of phenolic acids (569 ± 20 μg/g) and flavonoids (6090 ± 253 μg/g) were obtained in F. ulmaria and R. micrantha samples, respectively. Hydrolysable tannins (e.g. tri and digalloyl HHDP glucose) were the main group of phenolic compounds in C. sativa and F. ulmaria samples, while flavonoids (e.g. (+)-catechin and procyanidin dimers and trimers) were the most abundant group in R. micrantha. Thus, the stronger effect showed by this latter against all the Candida species (MIC ≤ 0.155 mg/mL) and, particularly its fungicide effects in C. glabrata, might be related to the mentioned flavonoids that were inexistence in the other samples.
Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers are a source of a variety of polyphenols. R. micrantha flowers extract had a strong effect on Candida species and particularly a fungicide effect in Candida glabrata. Procyanidins could be related to that fungicide effects.Figure optionsDownload as PowerPoint slideHighlights
► Castanea sativa, Filipendula ulmaria and Rosa micrantha flowers present several polyphenols.
► R. micrantha flowers extract had a strong effect on Candida species.
► R. micrantha flowers extract revealed fungicide effect in Candida glabrata.
► Procyanidins could be related to the fungicide effects.
Journal: Industrial Crops and Products - Volume 44, January 2013, Pages 104–110