کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4521224 | 1625182 | 2011 | 10 صفحه PDF | دانلود رایگان |

The aqueous, ethyl acetate, methanolic and Total Oligomer Flavonoids (TOF) enriched extracts, obtained from the aerial parts of Cyperus rotundus, were investigated for their contents in phenolic compounds. Antioxidative activity using the NBT/riboflavin assay system, antimicrobial activity against Gram positive and Gram negative bacterial reference strains as well as antigenotoxic activity tested with the SOS chromotest assay were also studied. Significant antibacterial activity against reference strains; Staphylococcus aureus, Enterococcus faecalis, Salmonella enteritidis and Salmonella typhimurium, was detected in the presence of ethyl acetate and TOF enriched extracts. In addition to their antimicrobial activity, the same extracts showed a significant ability to inhibit nitroblue tetrazolium reduction by the superoxide radical in a non enzymatic O2.− generating system, and were also able to reduce significantly the genotoxicity induced by nifuroxazide and Aflatoxin B1. The antioxidant, antimicrobial and antigenotoxic activities exhibited by C. rotundus depend on the chemical composition of the tested extracts.
Research Highlights
► We determined phenolic content of C. rotundus aerial part extract.
► Significant antibacterial activity was detected with ethyl acetate and TOF enriched extracts.
► Same extracts showed a significant ability to inhibit superoxide radicals.
► These extracts were able to reduce significantly the genotoxicity induced by genotoxic AFB1 and NF.
► We established correlations between tested activities and chemical composition.
Journal: South African Journal of Botany - Volume 77, Issue 3, August 2011, Pages 767–776