کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
4622317 1339497 2007 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Asymptotic behavior of distributions of mRNA and protein levels in a model of stochastic gene expression
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات آنالیز ریاضی
پیش نمایش صفحه اول مقاله
Asymptotic behavior of distributions of mRNA and protein levels in a model of stochastic gene expression
چکیده انگلیسی

The paper is devoted to a stochastic process introduced in the recent paper by Lipniacki et al. [T. Lipniacki, P. Paszek, A. Marciniak-Czochra, A.R. Brasier, M. Kimmel, Transcriptional stochasticity in gene expression, J. Theor. Biol. 238 (2006) 348–367] in modelling gene expression in eukaryotes. Starting from the full generator of the process we show that its distributions satisfy a (Fokker–Planck-type) system of partial differential equations. Then, we construct a c0 Markov semigroup in L1 space corresponding to this system. The main result of the paper is asymptotic stability of the involved semigroup in the set of densities.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Mathematical Analysis and Applications - Volume 333, Issue 2, 15 September 2007, Pages 753-769