کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4754896 | 1361490 | 2017 | 52 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Insulin-like plant proteins as potential innovative drugs to treat diabetes-The Moringa oleifera case study
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی شیمی
بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Insulin-like plant proteins as potential innovative drugs to treat diabetes-The Moringa oleifera case study Insulin-like plant proteins as potential innovative drugs to treat diabetes-The Moringa oleifera case study](/preview/png/4754896.png)
چکیده انگلیسی
Various plant species have long been used in traditional medicine worldwide to treat diabetes. Among the plant-based compounds with hypoglycemic properties, studies on insulin-like proteins isolated from leaves, fruits and seeds are rarely reported in the relevant literature. Our research group has been investigating the presence of insulin-like proteins in Moringa oleifera, a plant species native to India, and we have obtained a leaf protein isolate and semi-purified derived fractions, as well as a seed coat protein fraction (Mo-SC), with hypoglycemic activity in chemically induced diabetic mice that have increased tolerance to orally administered glucose. Equally importantly, Mo-SC possesses insulin-like antigenic epitopes. In this context, the present review aims to highlight that prospection of insulin-like proteins in plants is of the utmost importance both for finding new drugs for the treatment of diabetes and for shedding light on the mechanisms involved in diabetes.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: New Biotechnology - Volume 39, Part A, 25 October 2017, Pages 99-109
Journal: New Biotechnology - Volume 39, Part A, 25 October 2017, Pages 99-109
نویسندگان
P.C. Paula, J.T.A. Oliveira, D.O.B. Sousa, B.G.T. Alves, A.F.U. Carvalho, O.L. Franco, I.M. Vasconcelos,