کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4760341 | 1421977 | 2017 | 8 صفحه PDF | دانلود رایگان |
- Characterization of a new tert-leucinate class synthetic cannabinoid.
- GC-EI-MS, HPLC-PDA, LCMS, ESI-HRMS and NMR data for 5F-MDMB-PICA.
- First identification of 5F-MDMB-PICA in “spice like” herbal incenses.
- IUPAC: methyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate.
- Synonyms in NPS market: 5F-MDMB-2201, MDMB-2201.
A brown powder and different product packages of “spice-like” herbal incenses were analyzed using a systematic identification approach based on liquid chromatography with diode array detector (HPLC-PDA) and gas chromatography mass spectrometry (GC-MS) with computer based library search against spectral libraries. However, the most predominant compound in the methanolic sample solutions could not be identified. In order to elucidate the chemical structure, a more extensive analysis of the material was initiated using liquid chromatography mass spectrometry (LC-MS), electrospray high resolution mass spectrometry (ESI-HRMS) and 1H, 13C and 19F nuclear magnetic resonance spectroscopy (NMR), which allowed the identification and characterization of the major compound as methyl 2-[[1-(5-fluoropentyl)indole-3-carbonyl]amino]-3,3-dimethyl-butanoate (5F-MDMB-PICA).The goal of this study is to provide analytical information for the identification of this new tert-leucinate class synthetic cannabinoid by various analytical methods.
Journal: Forensic Science International - Volume 273, April 2017, Pages 45-52