کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
4933775 | 1433800 | 2016 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Low serum prealbumin levels in post-stroke depression
ترجمه فارسی عنوان
سطح پلاسبومین پایین سرم در افسردگی پس از سکته مغزی
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
افسردگی، سکته مغزی پیش آلبومین
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
روانپزشکی بیولوژیکی
چکیده انگلیسی
Previous studies have shown that prealbumin is associated with depression. However, the association between prealbumin and post-stroke depression remains unelucidated. This observational cohort study determined whether low baseline serum prealbumin could predict post-stroke depression at 1 month in patients admitted with acute stroke. The study, conducted from October 2013 to September 2014, included 307 patients with acute stroke who were followed-up for 1 month. Serum prealbumin was measured within 24 h after admission using an immunoturbidimetric method. The17-item Hamilton Depression Scale was used to evaluate depression symptoms. Patients with a depression score of â¥7 were evaluated using the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, 4th edition, for diagnosing post-stroke depression at 1 month. Binary logistic regression analysis was used to evaluate possible predictors of post-stroke depression. Overall, 93 (30.3%) patients were diagnosed with post-stroke depression. Serum prealbumin was significantly lower in patients with versus those without post-stroke depression, and was a significant predictor of post-stroke depression after adjusting for confounding risk factors. In conclusion, baseline serum prealbumin level was associated with post-stroke depression at 1 month, suggesting that prealbumin might be a useful biomarker for post-stroke depression.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Psychiatry Research - Volume 246, 30 December 2016, Pages 149-153
Journal: Psychiatry Research - Volume 246, 30 December 2016, Pages 149-153
نویسندگان
Liping Wang, Huiqin Xu, Wenwei Ren, Lin Zhu, Yaling Chang, Yingying Gu, Mengjiao Yan, Jincai He,