Cell-targeted, dual reduction- and pH-responsive saccharide/lipoic acid-modified poly(L-lysine) and poly(acrylic acid) polyionic complex nanogels for drug delivery

A cell-targeted, reduction-/pH-responsive polyionic complex (PIC) micelle system was developed by simply mixing cationic PLL-g-(Lipo-Lac) and anionic PAA for intracellular drug delivery.