کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5030881 1470936 2017 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Metal carbonyl-gold nanoparticle conjugates for highly sensitive SERS detection of organophosphorus pesticides
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Metal carbonyl-gold nanoparticle conjugates for highly sensitive SERS detection of organophosphorus pesticides
چکیده انگلیسی
The binding of organometallic osmium carbonyl clusters onto the surface of gold nanoparticles (10OsCO-Au NPs) greatly enhanced the CO stretching vibration signal at ~2100 cm−1, which is relatively free from interference due to the absorbance of biomolecules. By utilizing the acetylcholinesterase (AChE) mediated hydrolysis of acetylthiocholine to thiocholine where the activity of AChE is inhibited by the presence of organophosphate pesticides (OPPs), the subsequent thiocholine-induced aggregation of 10OsCO-Au NPs can be monitored by the change in color of the NPs solution and the variation in intensity of the SERS CO signal. The change in color offers a fast pre-screening method, whereas monitoring via SERS is used for greater accuracy and lower limit of detection (0.1 ppb) for quantitative detection. Its potential as a quick and accurate method of OPPs monitoring in consumer products was demonstrated in the detection of OPPs in real spiked samples such as beer.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosensors and Bioelectronics - Volume 96, 15 October 2017, Pages 167-172
نویسندگان
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