Characterization of micro-resonator based on enhanced metal insulator semiconductor capacitor for glucose recognition

- The characterization of the micro-resonator incorporating MIS capacitor for glucose detection implemented on the standard solution of d-glucose and the serum.
- Discrepancy in complex permittivity was implemented for variation of the MIS capacitance which indeed results for the level of glucose concentration detection.
- Minimum detectable glucose level of 7.45 mg/dl with good linearity among the concentrations.
- The MIS based capacitive sensing has been validated with the best resolution of 112.38 × 10−3 pF/mg/dl.

We present a concept for the characterization of micro-fabricated based resonator incorporating air-bridge metal-insulator-semiconductor (MIS) capacitor to continuously monitor an individual's state of glucose levels based on frequency variation. The investigation revealed that, the micro-resonator based on MIS capacitor holds considerable promise for implementation and recognition as a glucose sensor for human serum. The discrepancy in complex permittivity as a result of enhanced capacitor was achieved for the detection and determination of random glucose concentration levels using a unique variation of capacitor that indeed results in an adequate variation of the resonance frequency. Moreover, the design and development of micro-resonator with enhanced MIS capacitor generate a resolution of 112.38 × 10−3 pF/mg/dl, minimum detectable glucose level of 7.45 mg/dl, and a limit of quantification of 22.58 mg/dl. Additionally, this unique approach offers long-term reliability for mediator-free glucose sensing with a relative standard deviation of less than 0.5%.