Alumina-sulfuric acid catalyzed eco-friendly synthesis of xanthenediones

Alumina-sulfuric acid has been developed as a cost-effective, recyclable, heterogeneous solid acid catalyst for the eco-friendly synthesis of 9-aryl-1,8-dioxododecahydroxanthenes and 9-aryl-3,3,6,6-tetramethyl-1,8-dioxooctahydroxanthenes through the condensation of cyclic 1,3-diketones with different aryl and heteroaryl aldehydes.

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► Alumina-sulfuric acid as recyclable cost-effective mild solid Bronsted acid catalyst.
► Eco-friendly synthesis of xanthenediones.
► Survival of acid-labile moieties.