کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5121957 1486846 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Registry-based randomized controlled trials- what are the advantages, challenges, and areas for future research?
ترجمه فارسی عنوان
محققان کنترل شده تصادفی مبتنی بر رجیستری - مزایا، چالش ها و زمینه های تحقیق در آینده چیست؟
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
چکیده انگلیسی

Registry-based randomized controlled trials are defined as pragmatic trials that use registries as a platform for case records, data collection, randomization, and follow-up. Recently, the application of registry-based randomized controlled trials has attracted increasing attention in health research to address comparative effectiveness research questions in real-world settings, mainly due to their low cost, enhanced generalizability of findings, rapid consecutive enrollment, and the potential completeness of follow-up for the reference population, when compared with conventional randomized effectiveness trials. However several challenges of registry-based randomized controlled trials have to be taken into consideration, including registry data quality, ethical issues, and methodological challenges. In this article, we summarize the advantages, challenges, and areas for future research related to registry-based randomized controlled trials.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Epidemiology - Volume 80, December 2016, Pages 16-24
نویسندگان
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