کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5133995 | 1492072 | 2017 | 7 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Development and characterization of phosphatidylcholine nanovesicles, containing garlic extract, with antilisterial activity in milk Development and characterization of phosphatidylcholine nanovesicles, containing garlic extract, with antilisterial activity in milk](/preview/png/5133995.png)
- Garlic extract was encapsulated into phosphatidylcholine liposomes.
- Nanoliposomes showed a mean diameter of 174.6Â nm and zeta potential of â16.2Â mV.
- Nanoliposomes containing garlic extract inhibited diverse strains of Listeria spp. in milk.
- Nanotechnology may be a useful strategy to delivery natural antimicrobials in food.
Phospholipid nanovesicles were developed to improve the stability of garlic (Allium sativum L.) extract. Electron microscopy of liposomes revealed nanometric and spherical-shaped vesicles with a mean particle size of 174.6 ± 17.3 nm and polydispersity index of 0.26 ± 0.02. The entrapment efficiency was 47.5 ± 7.3% and the nanoliposomes had a zeta potential of â16.2 ± 5.5 mV. The antimicrobial activity of free and encapsulated garlic extract was evaluated against different strains of Listeria spp. in milk at 37 °C for 24 h. For free and encapsulated garlic extracts at 5% concentration, a decrease of 4 log cycles in viable cell counts was observed at 10 h, against four of the five strains of Listeria spp. tested. The results indicate that liposomes constitute a suitable system for encapsulation of unstable garlic active compounds and the encapsulation of garlic extract proves to be a promising technology for multiple applications, including antimicrobial agents.
Journal: Food Chemistry - Volume 220, 1 April 2017, Pages 470-476