کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5136379 1494011 2017 24 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dispersive micro solid phase extraction of amantadine, rimantadine and memantine in chicken muscle with magnetic cation exchange polymer
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Dispersive micro solid phase extraction of amantadine, rimantadine and memantine in chicken muscle with magnetic cation exchange polymer
چکیده انگلیسی
This study demonstrated a novel dispersive micro solid phase extraction (DMSPE) method for extraction of adamantane drugs (amantadine, rimantadine and memantine) in chicken muscle. The adamantane drugs were extracted from chicken muscle using 1% acidic acetonitrile as extraction solvent. The cleanup of fatty matrices from analytes was achieved by the DMSPE technique using magnetic cation exchange polymer as adsorbent. In this procedure, the experimental parameters and conditions were optimized in detail for the improvement of extraction efficiency. The method showed low limit of detection of 0.03 μg/kg and recoveries of the analytes ranged from 87.2% to 109.3% for adamantane drugs. The proposed DMSPE method proved to be simple, effective and suitable for the treatment of adamantane drugs in chicken muscle with a relatively shorter extraction time.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography B - Volume 1051, 15 April 2017, Pages 92-96
نویسندگان
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