کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5137324 | 1494529 | 2017 | 8 صفحه PDF | دانلود رایگان |
- A lupin concentrate and a skimmed milk powder tested on lipids and cardiovascular risk factors.
- Randomised, parallel, double-blind, single-centre study, 12-week intervention.
- Reductions of LDL-C, non-HDL-C, and PCSK9 significant only after the lupin diet.
- Significant reduction of HDL-C concentration only observed after the milk diet.
The study had the objective of evaluating the effects of a lupin protein concentrate on plasma lipids and other cardiovascular risk factors, e.g. blood pressure and insulin resistance, compared to a skimmed milk powder. Fifty subjects followed a randomised, parallel, double-blind, single-centre study, consisting in a 12-week intervention: half of the participants consumed a lupin protein concentrate (30Â g/day of protein), the other half a lactose-free skimmed milk powder (30Â g/day of protein), both integrated into a mixed low-lipid diet. At the end of intervention, both groups showed similar reductions of total cholesterol concentrations versus baseline (â6.7%, and â7.2%, respectively), but the reductions of LDL-cholesterol (â8.0%), non-HDL-cholesterol (â7.5%), and proprotein convertase subtilisin/kexin type 9 (PCSK9) (â12.7%) levels were statistically significant only after the lupin diet. A significant reduction of HDL-cholesterol concentration was observed only after the milk diet. The differences between the two groups, however, were not statistically significant.
Journal: Journal of Functional Foods - Volume 37, October 2017, Pages 8-15