pH-Dependence of the thermal stability of metallo-DNA duplexes containing ligand-type 5-hydroxyuracil nucleobases

pH-Dependence of the thermal stability of metallo-DNA duplexes containing ligand-type 5-hydroxyuracil nucleobases (UOH). (left) Schematic representation of a metallo-DNA duplex containing metal-mediated 5-hydroxyuracil base pairs (UOH-M-UOH). (right) pH-Dependent formation of UOH-M-UOH base pairs and metal complexation of UOH-A base pairs.84