Antiparasitic activity against trypanosomatid diseases and novel metal complexes derived from the first time characterized 5-phenyl-1,2,4-triazolo[1,5-a]pyrimidi-7(4H)-one

Isostructural complexes with general formula [M(ftpO)2(H2O)4] have been obtained from reaction between triazolopyrimidine derivative 5-phenyl-1,2,4-triazolo[1,5-a]pyrimidi-7(4H)-one (HftpO) and first row transition nitrates. HftpO and their complexes have been characterized by spectroscopic and thermal analysis and X-ray diffraction. Antiparasitic activity of HftpO against Trypanosomatidae family strains has been studied.85