Transition-metal norharmane compounds as possible cytotoxic agents: New insights based on a coordination chemistry perspective

Copper, Nickel, Cobalt and Zinc compounds with the ligand norharmane and with 2,2′-bipyridyl (bpy) and 1,10-phenanthroline (phen) as co-ligands are presented, including a 3D structure. Evidence for cell growth inhibitory effects in two different cancer cell lines in vitro, are presented.