Crucial residue Trp158 of lipoprotein PiaA stabilizes the ferrichrome-PiaA complex in Streptococcus pneumoniae

PiaA is a surface-exposed lipoprotein of pneumococcal iron acquisition ATP binding cassette (PiaABC). Trp158 is a significant residue of PiaA for ferrichrome (Fc) binding and plays an important role in stabilizing the complex of PiaA and Fc in Streptococcus pneumoniae.199