Copper (II) and zinc (II) complexes with flavanone derivatives: Identification of potential cholinesterase inhibitors by on-flow assays

Synthesis of 17 flavanone-metal complexes and their subsequent evaluation by A Liquid Chromatography-Immobilized Capillary Enzyme Reactor-by UV detection (LC-ICER-UV) assay methodology indicated that nine of these complexes exhibited high acetylcholinesterase (AChE) inhibitory activity.82