Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors

Synthesis, biological evaluation and molecular modeling study of new (1,2,4-triazole or 1,3,4-thiadiazole)-methylthio-derivatives of quinazolin-4(3H)-one as DHFR inhibitors

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic Chemistry - Volume 72, June 2017, Pages 282-292

Yomna I. El-Gazzar, Hanan H. Georgey, Shahenda M. El-Messery, Heba A. Ewida, Ghada S. Hassan, Marwa M. Raafat, Menna A. Ewida, Hussein I. El-Subbagh,