Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition

Discovery of renin inhibitors containing a simple aspartate binding moiety that imparts reduced P450 inhibition

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 27, Issue 21, 1 November 2017, Pages 4838-4843

Brian G. Lawhorn, Tritin Tran, Victor S. Hong, Lisa A. Morgan, BaoChau T. Le, Mark R. Harpel, Larry Jolivette, Elsie Diaz, Benjamin Schwartz, Jeffrey W. Gross, Thaddeus Tomaszek, Simon Semus, Nestor Concha, Angela Smallwood, Dennis A. Holt,