Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazoles

Identification of the minimum PAR4 inhibitor pharmacophore and optimization of a series of 2-methoxy-6-arylimidazo[2,1-b][1,3,4]thiadiazoles

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 26, Issue 22, 15 November 2016, Pages 5481-5486

Kayla J. Temple, Matthew T. Duvernay, Jae G. Maeng, Anna L. Blobaum, Shaun R. Stauffer, Heidi E. Hamm, Craig W. Lindsley,